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  1. Pellois, J. P, Wang, W. and Gao, X. (2000) Peptide synthesis based on t-Boc chemistry and solution photogenerated acids. J. Comb. Chem. 2, 349-354. [Abstract]
  2. LeProust, E., Pellois, J. P, Yu, P., Zhang, H., Srivannavit, O., Gulari, E., Zhou, X., and Gao, X. (2000) Combinatorial screening method for synthesis optimization on a digital light-controlled microarray platform. J. Comb. Chem. 2, 355-360.
  3. Leproust E., Pearson C., Sinden R., and Gao, X. (2000) Unexpected formation of parallel duplex in GAA and CTT trinucleotide repeats of Friedreich's ataxia. J. Mol. Biol. 302, 1063-1080.[Abstract]
  4. Wang, W., Yu, P., Zhang, H., Yang, X., Liang, T.-C., and Gao, X. (2001) Synthesis and characterization of a tetranucleotide containing alternating phosphonate-amide backbone linkages. Bioorg. Med. Chem. 9, 107-119.[Abstract]
  5. LeProust,E., Zhang, H., Yu, P., Gao, X., Xiang, X., and Zhou, X. (2001) Characterization of oligodeoxyribonucleotide synthesis on glass plates. Nucleic Acids Res. 29, 2171-2180.[Abstract]
  6. Han, X. and Gao, X. (2001) Sequence specific recognition of ligand-DNA complexes studied by NMR. Cur. Med. Chem. Review. 8, 551-579. [Abstract]
  7. Gao, X., LeProust, E., Srivannavit, O., Gulari, E., and Zhou, X (2001) Flexible DNA chip synthesis gated by deprotection using solution photogenerated acids. Nucleic Acids Res. 29, 4744-4750.[Abstract]
  8. Nagaswamy, U., Gao, X., Martinis, S. A., and Fox, G. E. (2001) NMR structure of a ribosomal RNA hairpin containing a conserved pentaloop. Nucleic Acids Res. 29, 5129-5239.[Abstract]
  9. Gao, X., Stassinopoulos, A., Ji, J., Kwon, Y., Bare, S., and Goldberg, I. H. (2002) Induced formation of a DNA bulge by a molecular wedge ligand - Post-activated neocarzinostatin chromophore. Biochemistry 41, 5131-5143.
  10. Pellois, J. P., Zhou, X., Srivannavit, O., Zhou, T., Erdogan, G., and Gao, X. (2002) Individually addressable parallel peptide synthesis on microchips. Nat. Biotechnol. 20, 922-926.[Abstract]
  11. David M. Cohen, Jingna Wei, E. O'Brian Smith, Xiaolian Gao, Michael J. Quast, and Louis Sokoloff (2002) A method for measuring cerebral glucose metabolism in vivo by 13C-NMR spectroscopy. Magnetic Resonance in Medicine. Vol 48, 1063-1067.[Abstract]
  12. Kwon, Y., Xi, Z., Kappen, L. S., Goldberg, I. H., and Gao, X. (2003) A New complex of post-activated neocarzinostatin chromophore with DNA. Bulge DNA binding from the minor groove. Biochemistry 42, 1186-1198. [Abstract]
  13. Xia, Y., Yee, A., Arrowsmith, C. H., and Gao, X. (2003) 1HC and 1HN Total NOE correlations in a single 3D NMR experiment. 15N and 13C time sharing in t1 and t2 dimensions for simultaneous data acquisition. J. Biomol. NMR 27, 193-203.[Abstract]
  14. Cohen, D. M., Guthrie, P. H., Gao, X., Sakai, R., and Taegtmeyer, H. (2003) Glutamine Cycling in Isolated Working Rat Heart. Am. J. Physiol. Endocrinol. Metabolism 285, E1213-E1216.[Abstract]
  15. Rouillard, J. M., Lee, W. Truan, G., Gao, X., Zhou, X. and Gulari, E. (2004) Gene2Oligo: Oligonucleotide design for in vitro gene synthesis. Nucleic Acids Res. 32, W176-180.[Abstract]
  16. Li, C., Xia, Y., Gao, X., and Gershon, P. D. (2004) Mechanism of RNA 2'-O-methylation: Evidence that the catalytic lysine acts to steer rather than deprotonate the target nucleophile. Biochemistry 43, 5680-5687.[Abstract]
  17. Xia, Y., Sudha Veeraraghavan, and Gao, X. (2004) (3,2)D GFT-NMR experiments for fast data collection from Proteins. J. Biomol. NMR 29, 467-476.[Abstract]
  18. Zhou, X., Cai, S., Hong, A., Yu, P., Sheng, N., Srivannavit, O., Yong, Q., Muranjan, S., Rouilard, J. M., Xia, Y., Zhang, X., Xiang, Q., Ganesh, R., Zhu, Q., Matejko, A., Gulari, E., and Gao, X. (2004) Microfluidic picoarray synthesis of oligodeoxynucleotides and simultaneously assembling of multiple DNA sequences. Nucleic Acids Res. 32, 5409-5417.
  19. Srivannavit, O., Gulari, M., Gulari, E., LeProust, E., Pellois, J. P., Gao, X., Zhou, X. (2004) Design and fabrication of microwell array chips for a solution-based, photogenerated acid-catalyzed parallel oligonuclotide DNA synthesis. Sensors and Actuators A. 116, 150-160.
  20. Jun, K.-Y., Xia, Y., Han, X., Zhang, H., Timchenko, L., Swanson, S. M., and Gao, X. (2004) 1H, 15N and 13C Chemical Shift Assignments of RNA Repeats Binding Protein - CUGBP1ab. J. Biomol. NMR 30, 371-372.
  21. Tian, J., Gong, H., Sheng, N., Zhou, X., Gulari, E., Gao, X., and Church, G. (2004) Accurate multiplex gene synthesis from programmable DNA chips. Nature 432, 1050-1054.[Abstract]
  22. Xia, Y., Legge, G., Jun, K.-Y., Qi, Y., Lee, H., and Gao, X. (2005) IP-COSY, a totally in-phase and sensitive COSY experiment. J. Mag. Chemistry 43, 372-379.[Abstract]
  23. Zhao, Q., Nagaswamy, U., Lee, H., Xia, Y., Huang, H.-C., Gao, X., and Fox, G. E. (2005) NMR Structure and Mg2+ binding of an RNA segment that underlies the L7/L12 stalk in the E. coli 50S ribosomal subunit. in press.
  24. Backer, S. C. et al. (2005) ˇ°The External RNA controls consortium: a progress reportˇ± Nature Methods 2, 731-734.[Abstract]
  25. Mulder, B. A., Anava, S., Yu, Pl, Lee, K. W., Nguyen, A., Murphy, J., Willson, R., Briggs, J. M., Gao, X., and Hardin, S. (2005) Nucleotide modification at the ?-phosphate leads to the improved fidelity of HIV-1 reverse transcriptase. Nucleic Acids Res. 33, 4865-4873.[Abstract]
  26. Zheng, L., Zhu, B., Gao, X. (2005) Parallel thermodynamic analysis of duplexes on oligo DNA microarray and its important usage in SNP analysis. West China J. Pharmaceutical Sciences. 20, 396-399.
  27. Zheng, L., Sheng, N., Gao, X. (2005) Cloning, characterization and expression in E. coli of cDNA of SH2 domain and SHP2 and their interaction with CagA. West China J. Pharmaceutical Sciences. 20, 286-290.
  28. Hua, Z., Xia, Y., Srivannavit, O., Rouillard, J.-M., Zhou, X., Gao, X., and Gulari, E. (2006) A versatile microreactor platform featuring a chemical-resistant microvalve array for addressable multiplex syntheses and assays. J. Micromech. Microeng. 16, 1433-1443.
  29. Anbanandam, A., Albarado, D. C., Nguyen, C. T., Gao, X., Halder, G., Veeraraghavan, S. (2006) Insights into TEF-1 activity from the solution structure of TEA domain. Proc. Natl. Acad. Sci. USA, 103, 17225-17230.
  30. Lee, H., Diavatis, T., Tennakoon, S., Yu, P. and Gao, X. (2007) Solution structure of DNA/RNA hybrid duplex with C8-propynyl 2'-deoxyadenosine modifications: Implication of RNase H and DNA/RNA duplex interaction. Biochim Biophys Acta. Nov 16; [Epub ahead of print]; 1769, 20-28.[Abstract]
  31. Sthler, P, Beier, M, Gao, X, Hoheisel, J. (2006) Another side of genomics: Synthetic biology as a means for the exploitation of whole-genome sequence information. J. Biotech. 124, 206-212.[Abstract]
  32. Zhu, Q., Hong, A., Sheng, N., Zhang, X., Jun, K.-Y., Srivannavit, O., Gulari, E., Gao, X., and Zhou, X. (2007) Microfluidic biochip for nucleic acid and protein analysis in Methods Mol. Biol. Vol. 381; Microarrays. Vol. I. Ed. Rampal, J. B., in press.
  33. Vainrub, A., Deluge, N., Zhang, X., Zhou, X., and Gao, X. (2007) Predicting DNA duplex stability on oligonucleotide array in Methods Mol. Biol. Vol. 381; Microarrays. Vol. II. Ed. Rampal, J. B., in press.
  34. Feng, J., Wong, K.-Y., Lynch, G. C., Gao, X., and Pettitt, B. M. (2007) Peptide conformations of a microarray surface-tethered epitope of the tumor suppressor p53. J. Physical Chem. 111, 13797-13806.[Abstract]
  35. Xia, Y., Zhu, Q., Veeraraghhavan, S., and Gao, X. (2008) Fast (4,3)D GFT-TS-NMR for NOESY of small to medium-sized proteins. J. Magn. Reson. Vol. 190, 142-148.[Abstract]
  36. Xia, Y., Moran, S., Nikonowicz, E. P., and Gao, X. (2007) Z-Restored spin echo 13C 1D spectrum of straight baseline free of hump, dip and roll. Magn. Reson. Chem. In press.
  37. Wan, J., Kang, S., Tang, C., Yan, J., Ren, Y., Liu, J., Gao, X., Banerjee, A., Ellis, L. B. M., and Li, T. (2007) Meta-prediction of phosphorylation sites with weighted voting and restricted grid search parameter selection. Nucleic Acids Res. In press.
  38. Gong, W., Zhou, D., Ren, Y., Wang, Y., Zuo, Z., Shen, Y., Xiao, F., Zhu, Q., Hong, A., Zhou, Z., Gao, X., and Li, T. (2008) PepCyber:P~PEP : A database of human protein-protein interactions mediated by phosphoprotein binding domains. Nucleic Acids Res. 36, D679-D683.
  39. Gu, P., Reid, J., Gao, X., Shaw, C. A., Creighton, C., Dugas, D. T., Tran, P. L., Zhou, X., Drabek, R., Steffen, D. L., Hoang, D., Weiss, M. K., Naghavil, A. O., El-daye, J., Kahn, M. F., Legge, G. B., Wheeler, D., Gibbs, R. A., Miller, J., Cooney, A. J., and Gunaratne, P. H. (2008) Novel microRNA candidates and miRNA-mRNA pairs in embryonic stem (ES) cells. Plos ONE. 3, e2578.[PMID: 18648548]
  40. He, P. A., Nie, Z., Chen, J., Chen, J., Lv, Z., Sheng, Q., Zhou, S., Gao, X., Kong, L., Wu, X., Jin, Y. and Zhang, Y. (2008) Identification and characteristics of microRNAs from Bombyx mori. BMC Genomics 9, 248.[PMID: 18507836]
  41. Xiao, F., Zuo, Z., Cai, G., Kang, S., Gao, X. and Li, T. (2008) miRecords: an integrated resource for microRNA-target interactions. Nucleic Acids Res.[PMID: 18996891]

 

Reviews and Book Chapters

  1. Zhu, G., Xia, Y., Lin, D., and Gao, X. (2004) TROSY-based correlation and NOE spectroscopy for NMR structural studies of large proteins?Ch. 5 in Methods in Molecular Biology/Molecular Medicine. Ed. Walker, J. M. 278, 57-78. Hamans, UK.[Abstract]
  2. Zhu, G., Xia, Y., Lin, D., and Gao, X. (2004) TROSY-based NMR experiments for the study of macromolecular dynamics and hydrogen bonding?Ch. 8 in Methods in Molecular Biology/Molecular Medicine. Ed. Walker, J. M. 278, 164-184. Hamans, UK.[Abstract]
  3. Gao, X. (2004) In situ parallel synthesis of addressable peptide microarrays? in Proceedings of the 7th China Peptide Symposium. Peptides. Biology and Chemistry. Eds. Du, Y-C.,
  4. Zhang, Y. S., and Tam, J. P. Shanghai Sicentific & Technology Publishers. pp. 29-33.
  5. Gao, X., Pellois, J. P., Kim, K., Na, Y. , Gulari, E., and Zhou, X. (2004) High density peptide microarrays. In situ synthesis and applications? Molecular Diversity. 8, 177-187. [Abstract]
  6. Gao, X., Gulari, E., and Zhou, X. (2004) In situ synthesis of oligonucleotide microarrays? Biopolymers. 73, 579-596. [Abstract]
  7. Gao et al. (2003) In situ synthesis of oligonucleotide microarrays. In Biopolymers.
  8. Gao et al. (2003) Peptide microchips. In Molecular Diversity.
  9. Gulari, E., Gao, X., and Zhou, X. (2003) Light directed massively parallel on-chip synthesis of peptide arrays with t-Boc chemistry? Proteomics 3, 2135-2141.[Abstract]
  10. Gao, X. (2002) In situ parallel synthesis of addressable peptide microarrays in Proceedings of the 7th China Peptide Symposium.
  11. Han, X. and Gao, X. (2001) Sequence specific recognition of ligand-DNA complexes studied by NMR?Cur. Med. Chem. Review. 8, 551-579.
  12. Gao, X., Huang, X., Smith, G. K., and Zheng, M. (1998) Structure and dynamics of single stranded nucleic acids containing trinucleotide repeats in Genetic Instabilities and Hereditary Neurological Diseases. Eds. Warren, S. T. and Wells, R. D., Academic Press, USA, 623-646.
  13. Huang, X. and Gao, X. (1998) Structure and dynamics of DNA CCG and CGG trinucleotide repeats in Solution, Motion, Interaction and Expression of Biological Macromolecules. Eds. Sarma, R. H., and Sarma, M. H., Adenine Press, 2, 221-234.
  14. Gao, X. (1995) Nuclear magnetic resonance spectroscopy: 3 Dimensional proton nuclear magnetic resonance in Encyclopedia of Analytical Science. Academic Press: London.

 

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